If an Office 365 Disaster Happened, What Would You Do?

A question none of us like to think about too much is what we would do if a natural or man-made disaster took out Office 365 and disrupted service for an extended period. The good news is that the way Microsoft has built out Office 365 into datacenter regions helps to limit the effect of any outage, but the fact still remains that something bad could happen. What would you do then?